Our research is focused on understanding the microbial and cellular events that take place during persistent bacterial infections. Areas of investigation include Bacterial Pathogenesis of Brucella spp. in swine, bovine, canine and human hosts; Translational Medicine developing novel anti-infective delivery platform to treat persistent bacterial and parasitic infections; Biosafety and Biodefense: illuminating molecular interactions between the human host and virulent Brucella, Francisella, Burkholderia and Yersinia spp.